Reconstructing limbs to improve movement and function

Compliant Limb Reconstruction: Co-engineering Body and Machine to Revolutionize Limb Salvage

NIH-funded research University of California Los Angeles · NIH-10473072

This study is exploring new ways to help people who have lost the use of their limbs due to injury or illness by creating bionic solutions that work smoothly with the body, aiming to improve movement and reduce pain for those affected.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10473072 on NIH RePORTER

What this research studies

This research aims to develop innovative methods for reconstructing limbs that have lost their function due to injury or disease. By integrating surgical techniques with mechanical design, the project focuses on creating bionic solutions that work in harmony with the body's natural structures. The approach, known as anatomics, emphasizes the importance of compliant (flexible) structures in the body, particularly joints, to restore healthy movement. Patients suffering from limb pathology may benefit from new treatments that enhance their quality of life and reduce pain.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have experienced limb injuries or diseases that impair their movement and function.

Not a fit: Patients with fully functional limbs or those who have already undergone successful limb reconstruction may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to advanced treatments that restore mobility and reduce pain for patients with limb dysfunction.

How similar studies have performed: Previous research in the field of bionics and limb reconstruction has shown promising results, indicating that this approach has the potential for significant advancements.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.