Reconnecting adolescent and young adult cancer survivors with follow-up care

Re-Engaging AYA Survivors in Cancer-Related Healthcare (REACH): A Sequential Multiple Assignment Randomized Trial (SMART)

NIH-funded research Children's Hosp of Philadelphia · NIH-11303339

This project tries a step-by-step program—starting with reminder texts and informational resources and adding more support for those who still need it—to help adolescent and young adult cancer survivors return to regular long-term follow-up care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionChildren's Hosp of Philadelphia NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11303339 on NIH RePORTER

What this research studies

You would be someone who had cancer as a child or teen and may have fallen away from yearly survivorship visits. First, you'll be randomly assigned to either a low-touch approach with reminder text messages and informational resources for a few weeks or to receive written information only. If you don't make an appointment, you'll be re-randomized to receive up to 16 weeks of more intensive or different support to help you schedule and attend follow-up care. The program uses survivorship care plans and digital health tools and adjusts the level of help based on what actually helps you re-engage.

Who could benefit from this research

Good fit: Ideal candidates are adolescent and young adult survivors of childhood cancer who are due for or have lapsed from recommended long-term follow-up care and can receive text messages or digital resources.

Not a fit: People who are already regularly attending long-term follow-up visits or those who cannot use phone- or text-based interventions may not gain benefit from this program.

Why it matters

Potential benefit: If successful, this could help young survivors stay connected to care so late effects or new problems are caught and treated earlier.

How similar studies have performed: Simple reminder texts and informational outreach have improved appointment keeping in other groups, but using a sequential, adaptive (SMART) approach to step up support is relatively new.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer SurvivorshipCancers
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.