Real-time imaging of lung function in infants on ventilators
Official title: Real-time EIT pulmonary imaging for infants requiring ventilatory therapy
Funded at Colorado State University · NIH-11127457 · Data updated 2026-11-12
This study is looking at a new way to help doctors take care of premature babies with breathing problems by using a special imaging technique that shows how well their lungs are working, so they can choose the best treatments to keep them safe and healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project start | July 1, 2024 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $647,431 |
| NIH project number | 5R01HD113290-02 |
| Project ID | NIH-11127457 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are premature infants diagnosed with bronchopulmonary dysplasia who require ventilatory support.
✕Less likely to help
Patients who are not premature or do not have bronchopulmonary dysplasia may not benefit from this research.
What this research studies
This research focuses on improving the management of bronchopulmonary dysplasia (BPD) in premature infants who require ventilatory support. It utilizes a non-invasive imaging technique called electrical impedance tomography (EIT) to provide real-time, three-dimensional images of lung function. By assessing ventilation and blood flow in the lungs, the study aims to guide clinicians in selecting the most effective treatment strategies for these vulnerable patients. The approach is designed to minimize the risks associated with current ventilation methods and improve overall outcomes.
Why it matters
Potential benefit: If successful, this research could lead to better individualized treatment plans for infants with BPD, potentially reducing long-term lung complications.
How similar studies have gone: While the use of EIT for lung imaging is a novel approach in this specific patient population, similar non-invasive imaging techniques have shown promise in other areas of respiratory care.
Where this research is happening
-
Colorado State University
Fort Collins, United States Active
Researchers
- Principal investigator: Mueller, Jennifer Lynn — Colorado State University
- Study coordinator: Mueller, Jennifer Lynn
Related research
Other NIH-funded projects on the same topics.
-
Executive Function Enhancement for Young Children with Down Syndrome
A caregiver-guided program for kids with Down syndrome aged up to 11 to strengthen their thinking skills during early childhood.
-
Center for Bat One Health: investigating bat health and spillover risk
A center in West Africa and the U.S. will study how bat biology and environmental stressors influence virus shedding and the chance of viruses jumping to people.
-
Center for Bat One Health Investigations and Outbreak Response
A national research center will study how bat stress from heat and human activity affects bat biology and viruses to understand spillover risks to people.
-
Center for Bat One Health Investigations, Research, and Outbreak Response
A center focused on how stressors like heat and human activity affect bats and the viruses they carry, to help prevent spillover to people.
-
Executive Function Support for Young Children with Down Syndrome
A caregiver-led program helps young children with Down syndrome build executive function skills during a 12-week period.
-
How malaria spreads and resists treatment in different parts of Burkina Faso
This project looks at how different mosquitoes, parasites, and human factors shape malaria risk across communities in Burkina Faso.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.