Real-time blood flow visualization during brain surgery
Official title: Dye-free, on-demand visualization of blood flow during cerebrovascular surgery
Funded at Vasoptic Medical, INC. · NIH-10598593 · Data updated 2026-11-12
This study is testing a new imaging system that helps brain surgeons see blood flow in real-time during surgeries, like fixing aneurysms, to make better decisions and improve patient recovery, all without needing any special dyes.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vasoptic Medical, INC. NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | April 1, 2022 |
| Project end | March 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $882,991 |
| NIH project number | 5R44NS124442-02 |
| Project ID | NIH-10598593 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing cerebrovascular surgeries, such as those with brain aneurysms or arteriovenous malformations.
✕Less likely to help
Patients who are not undergoing neurosurgical procedures or those with conditions that do not involve blood flow monitoring may not benefit from this research.
What this research studies
This research focuses on developing a new imaging system that allows neurosurgeons to visualize blood flow in real-time during delicate brain surgeries, such as aneurysm clipping. The proposed system, called CVSurgeONTM, integrates with existing surgical microscopes and uses advanced laser speckle contrast imaging technology to provide non-invasive, quantitative information about blood flow in the surgical field. By eliminating the need for contrast agents, this approach aims to enhance surgical decision-making and improve patient outcomes. The technology has been validated in animal models, paving the way for potential use in human surgeries.
Why it matters
Potential benefit: If successful, this research could significantly improve the safety and effectiveness of cerebrovascular surgeries by providing surgeons with critical real-time blood flow information.
How similar studies have gone: Previous research has shown success with similar imaging technologies in animal models, indicating potential for effective application in human surgeries.
Where this research is happening
-
Vasoptic Medical, INC.
Baltimore, United States Active
Researchers
- Principal investigator: Rege, Abhishek — Vasoptic Medical, INC.
- Study coordinator: Rege, Abhishek
Related research
Other NIH-funded projects on the same topics.
-
Imaging eye blood flow to guide tiny glaucoma surgeries
A new imaging approach helps surgeons see eye blood flow during minimally invasive glaucoma surgery to improve outcomes for adults with glaucoma.
-
Noninvasive retinal biomarker for early cognitive impairment
A study to test a quick eye-based test that might detect early brain changes linked to dementia.
-
Measuring blood flow in the eye to assess glaucoma
This study is looking at a new imaging tool called XyCAM RI to see how it can help doctors understand blood flow in the eyes of people with glaucoma, especially those who are very nearsighted, so they can improve how glaucoma is diagnosed and treated.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.