Rapid nasal test to guide asthma treatment
Official title: NOVEL DIAGNOSTIC FOR MANAGING ASTHMA AT POINT OF CARE
Funded at Glycodots, LLC · NIH-11177842 · Data updated 2026-11-12
A quick nasal swab test that looks for a protein tied to eosinophilic asthma so patients can get more targeted treatment during a clinic visit.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Glycodots, LLC NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | September 1, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $287,829 |
| NIH project number | 5R43HL176373-02 |
| Project ID | NIH-11177842 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with asthma (including children able to provide a nasal swab) or those with suspected eosinophilic airway inflammation would be the ideal candidates to participate.
✕Less likely to help
Patients whose asthma is not driven by eosinophilic inflammation, people with other lung diseases, or those unable to provide a nasal swab are unlikely to benefit from this specific test.
What this research studies
You would give a simple nasal swab that the team would test for eosinophil peroxidase (EPX), a protein linked to a common, treatable form of asthma. The project is building a rapid point-of-care test that aims to give results similar to the existing lab-based EPX ELISA but without sending samples to a central lab. Researchers will compare results from the new rapid test to their gold-standard EPX-ELISA using human nasal swabs. If the rapid test matches the ELISA, clinicians could use it in clinic visits to identify eosinophilic inflammation and adapt treatment right away.
Why it matters
Potential benefit: If successful, patients could receive a noninvasive, same-visit test to identify eosinophilic asthma and help clinicians choose the most appropriate therapies faster.
How similar studies have gone: The team has a validated lab EPX-ELISA as a gold standard, but a rapid point-of-care EPX test is new and not yet available commercially.
Where this research is happening
-
Glycodots, LLC
San Diego, United States Active
Researchers
- Principal investigator: Svarovsky, Sergei a — Glycodots, LLC
- Study coordinator: Svarovsky, Sergei a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.