Rapid diagnosis of leptospirosis using leptospiral VM protein detection
Leptospiral VM Protein Antigen Detection for Rapid Diagnosis of Leptospirosis
['FUNDING_OTHER'] · LUNA BIOSCIENCE, INC. · NIH-11085136
This study is working on a quick test to help doctors easily find out if someone has leptospirosis, a serious infection, so they can start treatment right away and avoid complications, especially in areas where this illness is common.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LUNA BIOSCIENCE, INC. (nih funded) |
| Locations | 1 site (WESTPORT, UNITED STATES) |
| Trial ID | NIH-11085136 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a diagnostic test for leptospirosis, a serious bacterial infection caused by Leptospira. The goal is to create a rapid, point-of-care test that can detect leptospiral antigens in body fluids such as blood and urine. By enabling early diagnosis, the test aims to facilitate timely antimicrobial treatment, potentially preventing severe complications associated with the disease. This is particularly important in regions where leptospirosis is endemic and often misdiagnosed due to non-specific initial symptoms.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals presenting with acute undifferentiated fever, particularly in endemic regions or following environmental events like flooding.
Not a fit: Patients with chronic leptospirosis or those who do not exhibit acute symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnosis of leptospirosis, improving patient outcomes and reducing mortality rates.
How similar studies have performed: Previous research has shown promise in developing rapid diagnostic tests for infectious diseases, indicating potential success for this approach.
Where this research is happening
WESTPORT, UNITED STATES
- LUNA BIOSCIENCE, INC. — WESTPORT, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHAURASIA, REETIKA — LUNA BIOSCIENCE, INC.
- Study coordinator: CHAURASIA, REETIKA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.