Rapid blood-stopping adhesive for surgery and patients on blood thinners
Official title: Hemostatic Bioadhesive Paste for Coagulation-Independent Rapid Control of Bleeding
Funded at Sanaheal, INC. · NIH-11196760 · Data updated 2026-11-12
A sticky, biocompatible paste designed to stop surgical bleeding within seconds, including for people taking blood thinners or with bleeding disorders.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sanaheal, INC. NIH-funded |
| Lab location | 1 site (Somerville, UNITED STATES) |
| Project start | September 25, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $1,249,317 |
| NIH project number | 5R44HL176351-02 |
| Project ID | NIH-11196760 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates would be people facing surgery with high bleeding risk, particularly those taking blood thinners or who have acquired von Willebrand disease.
✕Less likely to help
People with only minor external bleeding, deep internal bleeds not accessible to topical treatment, or known allergies to adhesive components may not benefit from this product as currently planned.
What this research studies
This project is refining a bioadhesive paste that seals bleeding sites without relying on normal blood clotting, aiming for very fast control of bleeding. The team previously saw rapid success in rat and pig models and is now optimizing the formula, safety testing, and manufacturing steps to meet FDA IDE requirements before human use. Work includes lab and additional animal testing, biocompatibility and stability checks, and documentation needed for regulatory clearance. The goal is to make a product surgeons can apply quickly during operations where traditional clot-based products often fail.
Why it matters
Potential benefit: If successful, this could let surgeons stop major bleeding much faster—especially in patients on anticoagulants or with clotting problems—potentially reducing transfusions and complications.
How similar studies have gone: Existing topical hemostats typically rely on clotting and can fail in anticoagulated patients, so this coagulation-independent adhesive is relatively novel and has shown promising animal results but has not yet been proven in humans.
Where this research is happening
-
Sanaheal, INC.
Somerville, United States Active
Researchers
- Principal investigator: Yuk, Hyunwoo — Sanaheal, INC.
- Study coordinator: Yuk, Hyunwoo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.