Rapid, bedside test for identifying UTI bacteria and antibiotic resistance
Official title: Multiplexed Assay for Point-of-Care UTI Diagnosis (ID/AMR)
Funded at Nanopathdx, INC. · NIH-11290730 · Data updated 2026-11-12
A quick, 15-minute point-of-care test from urine samples to identify UTI germs and key antibiotic resistance markers, helping doctors choose the right treatment sooner.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nanopathdx, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2027 |
| Funding year | 2026 |
| Award (this year) | $919,857 |
| NIH project number | 5R44AI181154-03 |
| Project ID | NIH-11290730 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals experiencing symptoms of a suspected UTI who would benefit from rapid species and resistance information to guide therapy.
✕Less likely to help
Patients with non-UTI conditions or those not requiring rapid antibiotic decision-making may not benefit.
What this research studies
This grant supports developing a one-use diagnostic cartridge and small reader that works at the patient’s side to detect UTI pathogens and resistance genes directly from urine in about 15 minutes. No PCR or complex lab steps are needed, which could shorten the time to targeted therapy. By speeding results, it may reduce unnecessary broad-spectrum antibiotics and help prevent the spread of resistance. The project builds on early data showing selective and robust detection in urine and other samples, with a focus on real-world clinical use. The work is centered on a specific infection—urinary tract infections—and the goal is to bring a fast, accurate test to patients and clinicians.
Why it matters
Potential benefit: If successful, patients with UTIs could get targeted treatment faster, reducing pain and complication risks.
How similar studies have gone: Preliminary data show promising performance; this approach has not yet become a standard bedside diagnostic.
Where this research is happening
-
Nanopathdx, INC.
Cambridge, United States Active
Researchers
- Principal investigator: Burklund, Alison — Nanopathdx, INC.
- Study coordinator: Burklund, Alison
Related research
Other NIH-funded projects on the same topics.
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A quick test to identify urinary tract infection pathogens and antibiotic resistance
This study is working on a quick and easy test that can tell you if you have a urinary tract infection and what antibiotics will work best, all from a urine sample in just 15 minutes, so you can get the right treatment faster and feel better sooner!
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.