NIH-funded research R15 grant

Rapid antibiotic choices in 30 minutes for bacterial infections

Official title: A rapid antibiotic susceptibility testing (AST) platform using multiplex static gradients

Funded at Catholic University of America · NIH-11360836 · Data updated 2026-11-12

A fast microfluidic test that helps doctors pick the right antibiotic within about half an hour for serious bacterial infections.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionCatholic University of America
NIH-funded
Lab location1 site (Washington, United States)
Project startMay 7, 2026
Project endApril 30, 2029
Funding year2026
Award (this year)$596,250
NIH project number1R15AI199916-01
Project IDNIH-11360836 on NIH RePORTER

Who could benefit from this research

Could help

People with suspected acute bacterial infections, such as sepsis, UTIs, and acute pneumonia, who need rapid antibiotic guidance.

Less likely to help

If an infection is caused by non-bacterial pathogens or if rapid testing is not feasible in a given setting, the device may not offer benefit.

What this research studies

This project aims to build a small, drop-in device that quickly shows which antibiotics work against a patient’s bacteria. By delivering results in about 30 minutes, it could guide immediate treatment for conditions like sepsis, UTIs, and lung infections. The team plans to compare multiple antibiotics and bacteria types to find the most accurate, fast method that clinics can use without specialized labs.

Why it matters

Potential benefit: Patients could get more effective, tailored antibiotics quickly, reducing side effects and resistance.

How similar studies have gone: There is ongoing work on rapid AST methods, but this platform aims for broader species testing and faster results.

Where this research is happening

  • Catholic University of America
    Washington, United States
    Active

Researchers

  • Principal investigator: Luo, Xiaolong — Catholic University of America
  • Study coordinator: Luo, Xiaolong

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.