Randomized approach to better care for patients with hereditary breast and ovarian cancer syndromes
Official title: Randomized Trial to Improve Care of Patients with Hereditary Cancer Syndromes
Funded at Healthpartners Institute · NIH-11294292 · Data updated 2026-11-12
A randomized trial aims to help people with HBOC or Lynch syndrome receive timely, guideline-based cancer prevention care through primary care and targeted referrals.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Healthpartners Institute NIH-funded |
| Lab location | 1 site (Bloomington, UNITED STATES) |
| Project start | April 1, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $648,180 |
| NIH project number | 5R01CA283332-03 |
| Project ID | NIH-11294292 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with HBOC or Lynch syndrome who have not yet fully received recommended prevention care and are managed in or via primary care settings.
✕Less likely to help
Patients not affected by HBOC or Lynch syndrome or those not engaging with primary care-based prevention services may see little direct benefit.
What this research studies
This project focuses on patients with hereditary cancer syndromes such as HBOC or Lynch syndrome who are at increased cancer risk. It plans to implement and test a primary care–centered strategy to improve access to evidence-based prevention and appropriate referrals to specialists. By bringing decision support and streamlined pathways into routine primary care visits, the study seeks to raise adherence to prevention guidelines and improve early detection. The team will measure changes in care quality, referral rates, and potentially cancer outcomes over time.
Why it matters
Potential benefit: If successful, patients could receive faster access to preventive care and referrals, potentially reducing cancer risk and catching cancers earlier.
How similar studies have gone: Prior work suggests care gaps exist and targeted primary care interventions can improve preventive care delivery, with potential for improved outcomes in similar hereditary cancer contexts.
Where this research is happening
-
Healthpartners Institute
Bloomington, United States Active
Researchers
- Principal investigator: O'connor, Patrick J — Healthpartners Institute
- Study coordinator: O'connor, Patrick J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.