Racial, ethnic, and socioeconomic differences in lupus outcomes
DP22-002 Racial/ethnic and socioeconomic disparities in biologic and clinical SLE outcomes
This project looks at why people with lupus (SLE) from different racial, ethnic, and income groups have different health outcomes using clinical data and biological samples from a diverse California cohort.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11129597 on NIH RePORTER |
What this research studies
If you join, you would be part of an ongoing group of over 450 people with lupus from the San Francisco area who are followed over time. Researchers collect medical records and physician exams, take blood and other biological samples for genetic and epigenetic testing, and do structured interviews about your symptoms, healthcare access, and daily life. The team links biological measures with social and clinical data to see how these factors relate to flares, organ damage, and longer-term outcomes. Findings are analyzed and shared to better understand and address outcome differences across racial, ethnic, and socioeconomic groups.
Who could benefit from this research
Good fit: Adults with a physician diagnosis of systemic lupus erythematosus (SLE), especially those living in San Francisco County or the Bay Area and from diverse racial, ethnic, and socioeconomic backgrounds.
Not a fit: People without SLE, those living outside the study’s recruitment area, or patients seeking immediate new treatments (since this is an observational cohort) are unlikely to get direct benefit from participation.
Why it matters
Potential benefit: If successful, this work could reveal biological and social drivers of worse lupus outcomes and help target more equitable care or interventions.
How similar studies have performed: The original California Lupus Surveillance Project and earlier CLUES work have produced important epidemiologic and molecular findings, but applying those findings to reduce disparities is still an emerging effort.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Dall'era, Maria — University of California, San Francisco
- Study coordinator: Dall'era, Maria
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.