Quercetin helps improve lung health in patients with COPD
Quercetin prevent airway epithelial remodeling and promote lung health in OPD
This study is looking at how quercetin, a natural substance, might help improve the health of the lungs in people with COPD by fixing damaged airway cells and making it easier for them to fight off infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10878742 on NIH RePORTER |
What this research studies
This research investigates how quercetin, a natural compound, can prevent harmful changes in the airway lining of patients with chronic obstructive pulmonary disease (COPD). The study focuses on understanding how quercetin can help restore normal function to airway cells that have been damaged or altered due to the disease. By analyzing the effects of quercetin on specific genes involved in lung health, researchers aim to identify pathways that can be targeted for treatment. The ultimate goal is to enhance lung health and reduce the impact of respiratory infections in COPD patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic obstructive pulmonary disease (COPD).
Not a fit: Patients with other respiratory conditions not related to COPD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve lung function and overall health for patients with COPD.
How similar studies have performed: Previous research has shown promising results with quercetin in other contexts, suggesting potential for success in this novel application for COPD.
Where this research is happening
Philadelphia, United States
- Temple Univ of the Commonwealth — Philadelphia, United States (Active)
Researchers
- Principal investigator: Sajjan, Umadevi Sivanappa — Temple Univ of the Commonwealth
- Study coordinator: Sajjan, Umadevi Sivanappa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.