NIH-funded research NIH-funded research

Pulmonary and systemic effects of PM2.5 exposure during Southeast Asia deployment

Official title: CMA:Pulmonary and Systemic Effects of Deployment Related Particulate Matter Exposures

Funded at Minneapolis VA Medical Center · NIH-11264807 · Data updated 2026-11-12

This project will follow Veterans exposed to fine airborne particles during Southeast Asia deployment to learn how those exposures relate to lung health and overall body function.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMinneapolis VA Medical Center
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startJanuary 1, 2020
Project endMarch 31, 2028
Funding year2027
NIH project number5I01BX004633-07
Project IDNIH-11264807 on NIH RePORTER

Who could benefit from this research

Could help

Veterans with known Southeast Asia deployment exposure, especially those with chronic cough, wheeze, or dyspnea and minimal smoking history.

Less likely to help

Veterans without exposure history or without respiratory symptoms and with significant smoking history may have limited relevance for this study.

What this research studies

Researchers will study a cohort of Veterans from SHADE to see how past PM2.5 exposure is linked to lung function and respiratory symptoms. They will recruit 280 SHADE participants with and without respiratory symptoms, focusing on non- or former-smokers with light smoking history, across four sites. The work aims to identify biophysical and clinical effects of PM exposure on pulmonary and systemic health, in relation to symptom history. Findings could illuminate early lung changes and systemic impacts from deployment-related air pollution.

Why it matters

Potential benefit: If successful, the project could improve understanding of how PM2.5 exposure affects lung and systemic health in Veterans, guiding better screening and care.

How similar studies have gone: Previous SHADE cohorts have linked PM exposure to respiratory outcomes, and this study builds on that foundation with a targeted sub-cohort.

Where this research is happening

  • Minneapolis VA Medical Center
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Wendt, Chris H — Minneapolis VA Medical Center
  • Study coordinator: Wendt, Chris H

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.