PTSD Genetics Consortium
Psychiatric Genomics Consortium for PTSD
This project combines genetic data from many people who experienced trauma to find gene patterns that help predict who develops PTSD.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11306044 on NIH RePORTER |
What this research studies
You would be part of a large effort that combines genetic data from many people who have experienced trauma, some with PTSD and some without. Researchers merge genome-wide data from many studies to spot genetic differences linked to PTSD and to build polygenic risk scores that estimate genetic vulnerability. The work uses existing genetic samples and clinical information from diverse ancestry groups to make results more applicable across populations. This effort focuses on genetic discovery rather than testing a new treatment or medication.
Who could benefit from this research
Good fit: Ideal participants include people with a history of significant trauma, both those diagnosed with PTSD and trauma-exposed individuals without PTSD, including individuals from diverse ancestral backgrounds.
Not a fit: People without any history of trauma or those seeking an immediate new therapy are unlikely to receive direct benefit from this genetics-focused work.
Why it matters
Potential benefit: If successful, this work could help identify people at higher genetic risk for PTSD and inform prevention, early support, or targeted treatment research.
How similar studies have performed: Prior Psychiatric Genomics Consortium work has already identified multiple PTSD-linked loci and produced polygenic scores, showing that this large-scale approach can yield actionable genetic findings.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Nievergelt, Caroline M — University of California, San Diego
- Study coordinator: Nievergelt, Caroline M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.