Psyllium with Meals for Children with IBS and Fructan Sensitivity
ASSESSING PSYLLIUM GIVEN WITH MEALS FOR FRUCTAN SENSITIVITY IN CHILDREN WITH IRRITABLE BOWEL SYNDROME
This project explores if adding psyllium to meals can help children with Irritable Bowel Syndrome who are sensitive to fructans, a type of carbohydrate.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11159484 on NIH RePORTER |
What this research studies
Irritable Bowel Syndrome (IBS) causes abdominal pain in many children, and certain foods called FODMAPs, like fructans, can make symptoms worse. While a low-FODMAP diet can help, it's often hard for children to follow and can lead to other health concerns. This work aims to find a simpler way to manage fructan sensitivity by seeing if psyllium, a type of fiber, can reduce pain when taken with meals. We know that fructans are fermented by gut bacteria, and this process might be different in children who are sensitive to them. Psyllium is a gentle fiber that has shown promise in reducing abdominal pain in children with IBS.
Who could benefit from this research
Good fit: Ideal candidates are children between 0-11 years old who have been diagnosed with Irritable Bowel Syndrome and experience symptoms related to fructan sensitivity.
Not a fit: Patients whose IBS symptoms are not related to fructan sensitivity or who do not experience abdominal pain may not receive benefit from this specific approach.
Why it matters
Potential benefit: If successful, this could offer children with IBS a simpler and more practical way to manage their fructan sensitivity without needing a strict, restrictive diet.
How similar studies have performed: Previous work has shown that psyllium can decrease abdominal pain in children with IBS, suggesting a foundation for this approach.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Chumpitazi, Bruno Pedro — Duke University
- Study coordinator: Chumpitazi, Bruno Pedro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.