Providing naloxone to individuals released from jail to prevent overdoses

Evaluating naloxone-on-release from incarceration as community overdose prevention

NIH-funded research University of California, San Diego · NIH-11083592

This study is looking at a program that gives a life-saving medication called naloxone to people when they leave the Los Angeles County Jail, helping them and their friends learn how to prevent opioid overdoses and stay safe, especially for those in underserved communities.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11083592 on NIH RePORTER

What this research studies

This research evaluates a program that provides naloxone, a medication that can reverse opioid overdoses, to individuals upon their release from the Los Angeles County Jail. The program aims to reduce the high risk of overdose deaths that these individuals face, particularly in the weeks following their release. By training them and their social circles on how to recognize and respond to overdoses, the initiative seeks to improve access to life-saving interventions, especially for underserved populations such as African Americans and Latinx individuals. The study will analyze the effectiveness of this approach in preventing opioid-related deaths.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who are being released from the Los Angeles County Jail and are at risk of opioid overdose.

Not a fit: Patients who are not involved with opioid use or who are not recently released from incarceration may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the number of opioid-related overdose deaths among recently incarcerated individuals.

How similar studies have performed: Previous interventions using naloxone distribution have shown success in reducing overdose deaths, indicating a promising approach for this novel application.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.