Protein markers linked to pancreatic cancer risk
Uncovering Causal Protein Markers to Characterize Pancreatic Cancer Etiology and Improve Risk Prediction
Researchers are looking for proteins in blood and pancreatic tissue that could help people at higher risk understand their chances of getting pancreatic cancer.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lsu Health Sciences Center NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-11458817 on NIH RePORTER |
What this research studies
This project uses blood tests, pancreatic ductal tissue samples, and genetic information to separate proteins that likely cause pancreatic cancer from those that only appear alongside it. The team will use genetic 'instruments' to reduce bias that can confuse usual biomarker studies and compare results across different sample types. They will combine these findings into improved risk prediction models aimed at better identifying people at high risk. The work draws on existing patient samples and large datasets and could guide who might benefit from earlier screening in the future.
Who could benefit from this research
Good fit: Ideal candidates include people with pancreatic cancer, those with a family history or genetic predisposition, and volunteers willing to provide blood or tissue samples for research.
Not a fit: People without pancreatic cancer risk factors or those needing immediate treatment for advanced disease are unlikely to receive direct benefit from this research.
Why it matters
Potential benefit: If successful, the work could produce protein-based markers that improve pancreatic cancer risk prediction and help identify people for earlier monitoring or screening.
How similar studies have performed: Prior studies have suggested candidate protein markers and have used genetic approaches, but results have been inconsistent, so this work applies stronger methods to try to clarify findings.
Where this research is happening
New Orleans, United States
- Lsu Health Sciences Center — New Orleans, United States (Active)
Researchers
- Principal investigator: Wu, Lang — Lsu Health Sciences Center
- Study coordinator: Wu, Lang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.