Protein markers linked to pancreatic cancer risk
Official title: Uncovering Causal Protein Markers to Characterize Pancreatic Cancer Etiology and Improve Risk Prediction
Funded at Lsu Health Sciences Center · NIH-11458817 · Data updated 2026-11-12
Researchers are looking for proteins in blood and pancreatic tissue that could help people at higher risk understand their chances of getting pancreatic cancer.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lsu Health Sciences Center NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project start | September 18, 2024 |
| Project end | February 28, 2030 |
| Funding year | 2025 |
| Award (this year) | $683,662 |
| NIH project number | 7U01CA293883-03 |
| Project ID | NIH-11458817 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include people with pancreatic cancer, those with a family history or genetic predisposition, and volunteers willing to provide blood or tissue samples for research.
✕Less likely to help
People without pancreatic cancer risk factors or those needing immediate treatment for advanced disease are unlikely to receive direct benefit from this research.
What this research studies
This project uses blood tests, pancreatic ductal tissue samples, and genetic information to separate proteins that likely cause pancreatic cancer from those that only appear alongside it. The team will use genetic 'instruments' to reduce bias that can confuse usual biomarker studies and compare results across different sample types. They will combine these findings into improved risk prediction models aimed at better identifying people at high risk. The work draws on existing patient samples and large datasets and could guide who might benefit from earlier screening in the future.
Why it matters
Potential benefit: If successful, the work could produce protein-based markers that improve pancreatic cancer risk prediction and help identify people for earlier monitoring or screening.
How similar studies have gone: Prior studies have suggested candidate protein markers and have used genetic approaches, but results have been inconsistent, so this work applies stronger methods to try to clarify findings.
Where this research is happening
-
Lsu Health Sciences Center
New Orleans, United States Active
Researchers
- Principal investigator: Wu, Lang — Lsu Health Sciences Center
- Study coordinator: Wu, Lang
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.