Protecting patients with kidney disease from infections that can be prevented by vaccines
Protecting Patients with Glomerular Disease from Vaccine-Preventable Infections
This study is looking at how well vaccines work to protect people with kidney disease from the flu and pneumonia, especially since they are more likely to get these infections, and it aims to find out how their immune systems respond to the vaccines.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11004355 on NIH RePORTER |
What this research studies
This research investigates how effective vaccines are in preventing influenza and pneumococcal infections in patients with glomerular disease, who are at a significantly higher risk for these infections. The study aims to understand the immune response to vaccines in this population, particularly considering factors like immunosuppressive medications and altered immune function. By addressing gaps in knowledge regarding vaccine effectiveness and administration frequency, the research seeks to improve infection prevention strategies for these vulnerable patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with glomerular disease, particularly those who are at risk for influenza and pneumococcal infections.
Not a fit: Patients without glomerular disease or those who are not at risk for vaccine-preventable infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccination strategies that significantly reduce the risk of serious infections in patients with glomerular disease.
How similar studies have performed: Previous studies have shown that vaccination can be effective in reducing infection rates in other high-risk populations, but this specific approach in glomerular disease patients is less explored.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Glenn, Dorey — Univ of North Carolina Chapel Hill
- Study coordinator: Glenn, Dorey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.