Protecting participant privacy in Alzheimer's imaging studies

Protecting the Confidentiality of Participants in Studies of Alzheimer's Disease and Related Dementias by Replacing Face Imagery in MRI

NIH-funded research Mayo Clinic Rochester · NIH-10878746

This study is testing a new way to keep your identity safe in Alzheimer's research by using a generic face in MRI scans instead of your own, so your personal health information stays private while still getting valuable data.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10878746 on NIH RePORTER

What this research studies

This research focuses on enhancing the confidentiality of participants in Alzheimer's disease studies by developing a method to replace facial imagery in MRI scans with a generic, average face. This innovative approach aims to prevent the risk of facial recognition software linking participants to their sensitive health information. By using a digital face 'transplant', the study seeks to maintain the integrity of MRI data while ensuring that individual identities remain protected. This method addresses growing concerns about privacy in publicly shared research data.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias who are participating in MRI imaging studies.

Not a fit: Patients who are not involved in MRI imaging studies or do not have a diagnosis of Alzheimer's disease or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly enhance the privacy and security of participants' health information in Alzheimer's studies.

How similar studies have performed: While the approach of using digital face transplants for MRI de-identification is novel, similar privacy-enhancing techniques have shown promise in other imaging studies.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.