Protecting kidney health in young children with spina bifida
Seattle Children's Urologic Management to Preserve Initial Renal Function Protocol for Young Children with Spina Bifida (UMPIRE Protocol) (Component C)
This project tries specific urologic care plans to protect kidney function in young children who have spina bifida.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Children's Hospital NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11403051 on NIH RePORTER |
What this research studies
As a parent, you would be asked to have your young child with spina bifida follow a standardized urologic care plan called UMPIRE. Doctors will schedule regular clinic visits and tests such as urine checks and kidney/bladder imaging, collect health information, and may adjust bladder management or medications to help protect the kidneys. The team will track kidney function over time to learn which approaches keep kidneys working best. Your child's health information and samples may be used to help design better care for other children with spina bifida.
Who could benefit from this research
Good fit: Ideal candidates are infants and young children with spina bifida who receive urologic care at Seattle Children’s or participating clinics.
Not a fit: Adults, people without spina bifida, or children whose kidney function is already severely damaged would not be expected to benefit directly from this protocol.
Why it matters
Potential benefit: If successful, this could help children with spina bifida keep their kidneys healthier for longer and reduce the need for more invasive treatments.
How similar studies have performed: Related urologic management approaches have shown promise in clinical practice and smaller studies, while this protocol applies a standardized approach prospectively.
Where this research is happening
Seattle, United States
- Seattle Children's Hospital — Seattle, United States (Active)
Researchers
- Principal investigator: Ahn, Jennifer — Seattle Children's Hospital
- Study coordinator: Ahn, Jennifer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.