Protecting infants from influenza through maternal vaccination

Infant Protection from Influenza through Maternal Influenza Immunization

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11101287

This study is looking at how getting the flu vaccine during pregnancy can help protect babies from the virus, and it aims to find out the best timing for the vaccine to make sure moms pass on the right antibodies to their little ones.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11101287 on NIH RePORTER

What this research studies

This research investigates how vaccinating pregnant women against influenza can protect their infants from the virus. It focuses on understanding the timing of the vaccination and how antibodies are transferred to infants through the placenta and breastmilk. By analyzing data from a large cohort of mother-infant pairs, the study aims to identify the best practices for maternal immunization to enhance infant protection against influenza. The findings could lead to improved vaccination strategies that benefit both mothers and their babies.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant women, particularly those in their second trimester, who are considering influenza vaccination.

Not a fit: Patients who are not pregnant or those who have already been vaccinated against influenza may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence of influenza in infants, leading to fewer severe cases and deaths.

How similar studies have performed: Previous research has shown that maternal vaccination can effectively protect infants from various infectious diseases, indicating a promising approach in this area.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.