NIH-funded research P01 program project

Protecting Gulf of Alaska communities from shellfish toxins

Official title: Knowledge Warding Against Toxin Levels

Funded at Sitka Tribe of Alaska · NIH-11387535 · Data updated 2026-11-12

This project combines shellfish toxin testing and community surveys to help reduce paralytic shellfish poisoning risk for coastal Alaska and Alaska Native residents.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionSitka Tribe of Alaska
NIH-funded
Lab location1 site (Sitka, United States)
Project startMarch 20, 2024
Project endFebruary 28, 2029
Funding year2026
Award (this year)$556,471
NIH project number5P01ES035551-03
Project IDNIH-11387535 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are residents of Gulf of Alaska coastal communities—especially Alaska Native people—who harvest, prepare, or regularly eat local shellfish.

Less likely to help

People who do not live near the Gulf of Alaska or who never consume local shellfish are unlikely to receive direct benefit.

What this research studies

You and your community will help guide a tribally led center that tests shellfish for paralytic shellfish poisoning (PSP) using laboratory methods like receptor binding assays and HPLC. The team will collect shellfish from Gulf of Alaska coastal communities and analyze toxin levels in a central lab run by the Sitka Tribe. Researchers will also talk with residents through interviews and surveys to learn about harvesting habits, local warnings, and community concerns. A Community Engagement Core will work with tribal partners to share results, support local monitoring, and promote safer harvesting practices.

Why it matters

Potential benefit: If successful, the work could lower PSP cases by improving local monitoring, warnings, and community-led prevention.

How similar studies have gone: Laboratory monitoring and community outreach have reduced shellfish toxin risks in other regions, but a tribally led, Alaska-specific center combining lab testing with surveys is relatively new.

Where this research is happening

  • Sitka Tribe of Alaska
    Sitka, United States
    Active

Researchers

  • Principal investigator: Feldpausch, Jeff — Sitka Tribe of Alaska
  • Study coordinator: Feldpausch, Jeff

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.