Protecting against many coronaviruses, including COVID-19
Understanding antibody responses and defining correlates of protection for endemic and pandemic coronavirus strains
['FUNDING_P01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11123404
This project aims to understand how our bodies create strong, lasting protection against different coronaviruses, including COVID-19, to help develop better vaccines.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11123404 on ClinicalTrials.gov |
What this research studies
Our bodies develop protection against viruses like COVID-19 through infection or vaccination, but this protection can vary. This project looks closely at the immune cells that make antibodies to understand what makes some responses strong and long-lasting against many types of coronaviruses. We hope to use this knowledge to design new vaccines that offer broad protection against both current and future coronavirus threats.
Who could benefit from this research
Good fit: This foundational research does not directly recruit patients, but future studies stemming from this work may seek individuals with different coronavirus infection or vaccination histories.
Not a fit: Patients not interested in contributing to vaccine development or understanding immune responses may not find direct benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new vaccines that protect against a wide range of coronaviruses, potentially preventing future pandemics and reducing the severity of existing ones.
How similar studies have performed: While individual components of this approach have shown promise, this comprehensive program aims to integrate these findings to develop broadly protective vaccines, representing a novel and ambitious effort.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SIMON, VIVIANA A — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: SIMON, VIVIANA A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.