Prostate Cancer Tumor Atlas
Human Prostate Tumor Atlas Center
Building a detailed map of prostate tumors using advanced imaging and molecular tests to improve understanding and care for men with prostate cancer, especially African American men.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11177024 on NIH RePORTER |
What this research studies
If I participate, researchers will collect past and new prostate tumor samples and my clinical information from Washington University and partner sites. They will use advanced spatial imaging and molecular methods, including ATAC-seq and other 'omics, to map cancer and nearby non-cancer cells in three dimensions and across time. The team will combine images, molecular profiles, and treatment history to create a searchable atlas of tumor architecture and cell interactions. The goal is to find patterns tied to treatment resistance, progression to metastatic castration‑resistant disease, and drivers of disparities affecting African American men.
Who could benefit from this research
Good fit: Ideal candidates are men with prostate cancer who can provide tumor tissue and clinical records, including African American men and those with localized, recurrent, or metastatic disease.
Not a fit: People without prostate cancer or those seeking immediate treatment changes should not expect direct medical benefit from participation.
Why it matters
Potential benefit: This work could help doctors personalize treatments and identify new targets for therapies for men with prostate cancer.
How similar studies have performed: Other human tumor atlas efforts have successfully mapped cancer tissues and informed research, but a comprehensive spatial prostate atlas with emphasis on African American disparities is largely novel.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Ding, Li — Washington University
- Study coordinator: Ding, Li
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.