PROMT: a patient questionnaire to measure how methamphetamine treatment affects daily life
Official title: Validation of a survey tool to evaluate patient-reported outcomes for new medications to treat methamphetamine use disorder: The PROMT Survey
Funded at Univ of Arkansas for Med Scis · NIH-11195542 · Data updated 2026-11-12
This project will try out a new questionnaire that asks people with methamphetamine use disorder how medications affect their symptoms and daily functioning.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Arkansas for Med Scis NIH-funded |
| Lab location | 1 site (Little Rock, United States) |
| Project start | September 30, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $226,693 |
| NIH project number | 5R21DA059630-02 |
| Project ID | NIH-11195542 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are adults with methamphetamine use disorder who are in or seeking treatment and who can complete surveys about their symptoms and daily functioning.
✕Less likely to help
People without methamphetamine use disorder, those not receiving any treatment, or those unable to complete questionnaires due to severe cognitive or language barriers are unlikely to benefit.
What this research studies
You would be asked to complete the PROMT survey about symptoms, cravings, mood, and how well you can do daily tasks while receiving treatment. Researchers will compare survey answers with clinical measures like reported drug use and urine drug screens to see which patient-reported changes match objective results. The team aims to validate the questionnaire so it can be used in future medication trials, including antibody treatments in development. A patient-focused measure could show meaningful improvements beyond full abstinence.
Why it matters
Potential benefit: If successful, this questionnaire could help drug developers and regulators recognize improvements in daily life and symptoms, making it easier to approve medications for methamphetamine use disorder.
How similar studies have gone: Patient-reported outcome tools have been used successfully in opioid treatment research, but a validated methamphetamine-specific PRO instrument is new.
Where this research is happening
-
Univ of Arkansas for Med Scis
Little Rock, United States Active
Researchers
- Principal investigator: Pro, George — Univ of Arkansas for Med Scis
- Study coordinator: Pro, George
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.