Promoting nerve regeneration in the spinal cord after injury
Multipronged approach to promote functional axonal regeneration in the spinal cord after injury
This study is exploring a new way to help nerve fibers in the spinal cord heal after an injury by using a special technique to activate nerve cells, and it's designed for anyone interested in finding better treatments for spinal cord injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Drexel University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10831917 on NIH RePORTER |
What this research studies
This research investigates ways to enhance the regeneration of nerve fibers in the spinal cord following injury. It focuses on using a technique called DREADD-mediated neuronal activation to stimulate nerve cells, which may help overcome barriers to recovery. The research will involve both laboratory experiments with nerve cell cultures and animal models of spinal cord injury to assess the effectiveness of this approach. By understanding how neuronal activation can promote nerve growth, the study aims to identify new treatment strategies for spinal cord injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced spinal cord injuries.
Not a fit: Patients with complete spinal cord injuries or those who are not adults may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve recovery and function for individuals with spinal cord injuries.
How similar studies have performed: Previous research has shown promise in using neuronal activation techniques for nerve regeneration, indicating potential for success in this approach.
Where this research is happening
Philadelphia, United States
- Drexel University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Tom, Veronica Jean — Drexel University
- Study coordinator: Tom, Veronica Jean
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.