Programming proteins to control cell behavior
Nanoscale programing of celluar and physiological phenotypes
['FUNDING_OTHER'] · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · NIH-11011527
This study is exploring how tiny, specially designed proteins can help control how our cells work in response to certain signals, which could lead to new treatments for conditions like Alzheimer's and cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PENNSYLVANIA STATE UNIV HERSHEY MED CTR (nih funded) |
| Locations | 1 site (HERSHEY, UNITED STATES) |
| Trial ID | NIH-11011527 on ClinicalTrials.gov |
What this research studies
This research focuses on developing nanoscale computing agents that can manipulate cellular functions in response to specific signals. By designing proteins that act as programmable devices, the study aims to control how cells behave in various medical conditions, including Alzheimer's disease and cancer. The approach involves creating proteins that can respond to different stimuli, such as light or small molecules, allowing for precise control over cellular activities. This innovative methodology could lead to new treatments by targeting the underlying mechanisms of diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or various types of cancer.
Not a fit: Patients with conditions unrelated to cellular signaling or those not diagnosed with Alzheimer's disease or cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to groundbreaking therapies that improve treatment outcomes for patients with Alzheimer's disease and cancer.
How similar studies have performed: Other research has shown promise in using engineered proteins for therapeutic purposes, indicating that this approach could be a significant advancement in the field.
Where this research is happening
HERSHEY, UNITED STATES
- PENNSYLVANIA STATE UNIV HERSHEY MED CTR — HERSHEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DOKHOLYAN, NIKOLAY — PENNSYLVANIA STATE UNIV HERSHEY MED CTR
- Study coordinator: DOKHOLYAN, NIKOLAY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, anti-cancer immunotherapy, anticancer immunotherapy