Problem-solving support for family caregivers of people with cancer

Problem-Solving Therapy for Cancer Caregivers: A Randomized Clinical Trial in Outpatient Palliative Care

NIH-funded research Washington University · NIH-11140327

This project offers problem-solving therapy to family caregivers of people receiving outpatient palliative cancer care to help reduce stress and improve coping.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11140327 on NIH RePORTER

What this research studies

If I am caring for a loved one with cancer seen in an outpatient palliative clinic, I may be offered problem-solving therapy as part of this study. Caregivers are randomly assigned to receive the therapy or usual care at several outpatient clinics in both urban and rural areas. The team will track caregiver psychological distress and well-being and will study what helps or hinders delivering this therapy in real clinic settings. The work is run by Washington University and partner sites across multiple locations.

Who could benefit from this research

Good fit: Adult family or unpaid caregivers of people with cancer who are receiving outpatient palliative care are the ideal participants for this study.

Not a fit: Caregivers who are not connected to outpatient palliative care clinics, cannot attend therapy sessions, or have severe cognitive or language barriers may not receive benefit from this intervention.

Why it matters

Potential benefit: If successful, this approach could lower caregiver stress and improve coping, which may also help caregivers better support patients.

How similar studies have performed: Problem-solving therapy has shown benefits for caregivers in other medical settings, but there is limited evidence specifically for outpatient palliative cancer care.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer TreatmentCancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.