NIH-funded research R01 grant

Proactive quit-smoking e-visit through your primary care clinic

Official title: Hybrid Type 1 Effectiveness-Implementation Trial of a Proactive Smoking Cessation Electronic Visit for Scalable Delivery via Primary Care

Funded at Medical University of South Carolina · NIH-11146398 · Data updated 2026-11-12

This project offers an automated electronic visit from your primary care clinic to help adult smokers get tailored quitting support and medication options.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina
NIH-funded
Lab location1 site (Charleston, United States)
Project startJanuary 19, 2022
Project endAugust 31, 2027
Funding year2025
Award (this year)$618,640
NIH project number5R01CA258669-04
Project IDNIH-11146398 on NIH RePORTER

Who could benefit from this research

Could help

Adult smokers (age 21 and older) who are patients at participating primary care clinics and are willing to use the clinic's electronic patient portal or communication system.

Less likely to help

People who do not have access to the clinic's patient portal, decline electronic communication, or have medical reasons that preclude recommended medications may not benefit from this approach.

What this research studies

You would be identified as a smoker in your clinic's electronic health record and sent an asynchronous e-visit that asks about your smoking history and readiness to quit. An algorithm uses your answers to recommend evidence-based treatments, such as counseling, nicotine replacement, or prescription medications, and can help arrange prescriptions or referrals. The e-visit is delivered proactively through participating primary care practices and includes follow-up contacts to check progress and confirm quitting. The team is also studying how the e-visit fits into clinic workflows so more patients can be reached.

Why it matters

Potential benefit: If successful, this could make it much easier for smokers to receive proven quitting support through their own primary care clinic and increase quit success.

How similar studies have gone: The research team completed a pilot showing initial promise, and other digital cessation programs have produced encouraging but variable results when scaled up.

Where this research is happening

  • Medical University of South Carolina
    Charleston, United States
    Active

Researchers

  • Principal investigator: Dahne, Jennifer Renee — Medical University of South Carolina
  • Study coordinator: Dahne, Jennifer Renee

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.