Primate tissue resource for understanding alcohol's effects
Monkey Alcohol Tissue Research Resource (MATRR)
['FUNDING_OTHER'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-11191803
This project collects and shares organs, brains, and data from monkeys that drank alcohol so researchers can better understand how long-term alcohol use harms the body and brain.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON HEALTH & SCIENCE UNIVERSITY (nih funded) |
| Locations | 1 site (PORTLAND, UNITED STATES) |
| Trial ID | NIH-11191803 on ClinicalTrials.gov |
What this research studies
From groups of monkeys that voluntarily self-administered alcohol, the resource banks high-quality frozen and fixed tissues collected at necropsy along with clinical chemistry, brain imaging, genomics, and behavioral data. Drinking patterns are categorized (low, binge, heavy, very heavy) to link exposure levels with biological changes. Qualified researchers can request specific tissues or custom preparations and access the accompanying datasets through a dedicated web resource. The resource supports translational studies that connect primate findings to human alcohol-related disease.
Who could benefit from this research
Good fit: People with a history of heavy or chronic alcohol use are the most relevant patient group for research that uses this resource.
Not a fit: People without any history of alcohol use or whose health issues are unrelated to alcohol are unlikely to directly benefit from studies using this resource.
Why it matters
Potential benefit: If successful, this resource could speed discovery of biological markers and treatment targets to prevent or reduce alcohol-related organ and brain damage.
How similar studies have performed: Primate tissue banks and animal models have previously enabled discoveries about alcohol-related brain and organ changes, so this builds on established approaches rather than being purely untested.
Where this research is happening
PORTLAND, UNITED STATES
- OREGON HEALTH & SCIENCE UNIVERSITY — PORTLAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GRANT, KATHLEEN A — OREGON HEALTH & SCIENCE UNIVERSITY
- Study coordinator: GRANT, KATHLEEN A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.