Preventing Wilson's disease by reducing copper buildup in the body
Reversal of copper accumulation for the early prevention of Wilson’s disease
['FUNDING_R21'] · UNIVERSITY OF MASSACHUSETTS LOWELL · NIH-10710203
This study is looking for a better way to help young children with Wilson's disease by safely removing extra copper from their livers, using new methods that are easier on their bodies than current treatments.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MASSACHUSETTS LOWELL (nih funded) |
| Locations | 1 site (LOWELL, UNITED STATES) |
| Trial ID | NIH-10710203 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new treatment approach for Wilson's disease, a genetic disorder that leads to harmful copper accumulation in the body. The study aims to safely remove excess copper from the liver, particularly in young children diagnosed early through family screening. By exploring innovative drug delivery methods, the research seeks to provide a more effective and less toxic alternative to current treatments, which often have significant side effects. The goal is to initiate treatment as early as possible to prevent severe liver damage.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with Wilson's disease, especially those identified early through family screening.
Not a fit: Patients with advanced liver disease or those who do not have Wilson's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer and more effective treatment option for patients with Wilson's disease, particularly benefiting children diagnosed at a young age.
How similar studies have performed: While there have been successful treatments for Wilson's disease, this approach is novel and aims to address the limitations of existing therapies.
Where this research is happening
LOWELL, UNITED STATES
- UNIVERSITY OF MASSACHUSETTS LOWELL — LOWELL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KIM, JONGHAN — UNIVERSITY OF MASSACHUSETTS LOWELL
- Study coordinator: KIM, JONGHAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.