NIH-funded research R01 grant

Preventing weight gain and blood sugar problems after kidney transplant

Official title: Prevention of Weight Gain and Impaired Glucose Metabolism Post Kidney Transplantation: A Pilot and Feasibility Study

Funded at University of Kansas Medical Center · NIH-11374419 · Data updated 2026-11-12

This project offers a diet and activity program for people who have had a kidney transplant to help prevent weight gain and problems with blood sugar.

More Kidney Transplantation research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Kansas Medical Center
NIH-funded
Lab location1 site (Kansas City, United States)
Project startApril 1, 2024
Project endMarch 31, 2027
Funding year2026
Award (this year)$310,000
NIH project number5R01DK137986-03
Project IDNIH-11374419 on NIH RePORTER

Who could benefit from this research

Could help

Adults who have recently received a kidney transplant and who can participate in a supervised diet and activity program are ideal candidates.

Less likely to help

People with established, insulin-treated diabetes at enrollment or those unable to follow dietary or activity guidance may not receive benefit from this prevention program.

What this research studies

If you've recently had a kidney transplant, researchers will invite you to join a pilot program that gives personalized dietary guidance and support for increased physical activity while they monitor your weight, body fat, and blood sugar over time. The team will use careful measurements and regular follow-up to compare outcomes with usual care and determine whether the program is workable for transplant patients. This is a small, rigorous pilot meant to test feasibility and refine the approach before a larger trial. The study is designed to address limitations of earlier studies that had mixed results and higher risk of bias.

Why it matters

Potential benefit: If successful, this could reduce post-transplant weight gain and lower the risk of developing diabetes, protecting your overall health and your transplanted kidney.

How similar studies have gone: Earlier small or lower-quality trials of diet or diet-plus-activity after transplant have had mixed results, so this more rigorous pilot seeks clearer evidence.

Where this research is happening

  • University of Kansas Medical Center
    Kansas City, United States
    Active

Researchers

  • Principal investigator: Jakicic, John M — University of Kansas Medical Center
  • Study coordinator: Jakicic, John M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.