Preventing the progression of pancreatic cancer
Preventing an Incurable Disease: The Prevention of Progression to Pancreatic Cancer Trial (The 3P-C Trial)
This study is looking to help people who have had surgery for a condition called IPMN by closely watching them over the years to catch any signs of pancreatic cancer early using special imaging techniques.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10694111 on NIH RePORTER |
What this research studies
This research focuses on improving outcomes for patients at risk of developing pancreatic cancer, particularly those with intraductal papillary mucinous neoplasms (IPMN). The trial involves monitoring patients who have undergone surgery for IPMN to identify any progression of the disease early. By employing advanced imaging techniques and a structured follow-up protocol, the study aims to detect changes in the pancreatic tissue that could indicate a higher risk of cancer development. Patients will be closely observed over several years to assess the effectiveness of these monitoring strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with intraductal papillary mucinous neoplasms (IPMN) and have undergone partial pancreatectomy.
Not a fit: Patients who do not have IPMN or have advanced pancreatic cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and intervention for pancreatic cancer, significantly improving survival rates.
How similar studies have performed: Previous research has shown promise in early detection strategies for pancreatic cancer, but this specific approach to monitoring IPMN is relatively novel.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Allen, Peter J — Duke University
- Study coordinator: Allen, Peter J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.