Preventing strokes in children with sickle cell anemia in Nigeria
Primary Prevention of Stroke in Children with Sickle Cell Anaemia in Nigeria: Community vs Teaching Hospital
['FUNDING_OTHER'] · BARAU DIKKO TEACHING HOSPITAL/ KADUNA STATE UNIVERSITY · NIH-10896201
This study is looking at ways to help prevent strokes in children with sickle cell anemia in Nigeria by comparing different treatment approaches in community and teaching hospitals, aiming to find the best way to keep these kids safe and healthy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BARAU DIKKO TEACHING HOSPITAL/ KADUNA STATE UNIVERSITY (nih funded) |
| Locations | 1 site (KADUNA, NIGERIA) |
| Trial ID | NIH-10896201 on ClinicalTrials.gov |
What this research studies
This research focuses on preventing strokes in children with sickle cell anemia (SCA) by implementing screening and treatment protocols in Nigeria. The study compares the effectiveness of stroke prevention strategies in community hospitals versus teaching hospitals. It involves screening children for abnormal transcranial Doppler (TCD) measurements and providing regular blood transfusions followed by hydroxyurea therapy. The goal is to significantly reduce the incidence of strokes in this vulnerable population.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years diagnosed with sickle cell anemia living in Nigeria.
Not a fit: Patients outside the age range of 0-11 years or those without a diagnosis of sickle cell anemia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could dramatically lower the risk of stroke in children with sickle cell anemia, improving their quality of life and long-term health outcomes.
How similar studies have performed: Previous research in high-resource countries has shown that similar stroke prevention strategies can reduce stroke incidence rates by up to 92%, indicating potential for success in this study.
Where this research is happening
KADUNA, NIGERIA
- BARAU DIKKO TEACHING HOSPITAL/ KADUNA STATE UNIVERSITY — KADUNA, NIGERIA (ACTIVE)
Researchers
- Principal investigator: BELLO-MANGA, HALIMA — BARAU DIKKO TEACHING HOSPITAL/ KADUNA STATE UNIVERSITY
- Study coordinator: BELLO-MANGA, HALIMA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.