Preventing sepsis-related deaths in children
Suspect Treat Organ failure Prevent Sepsis Mortality (STOP Sepsis Mortality)
This study is looking at how to better diagnose and treat sepsis in children by understanding how their bodies react to infections, with the goal of finding quick and effective treatments to help save lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Research Institute NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-11020157 on NIH RePORTER |
What this research studies
This research focuses on improving the diagnosis and treatment of pediatric sepsis, a severe condition that can lead to organ failure and death in children. It aims to understand the different ways sepsis can present in young patients and how their immune systems respond to infections. By utilizing advanced techniques, including artificial intelligence and studying cellular energy processes, the research seeks to identify effective treatments that can be administered quickly to save lives. The project will also explore the role of mesenchymal stem cells in enhancing cellular energy and reducing inflammation.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are at risk of or diagnosed with sepsis.
Not a fit: Patients who are not within the pediatric age range or those with conditions unrelated to sepsis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the mortality rate of sepsis in children, particularly in underserved populations.
How similar studies have performed: Previous research has shown promise in improving sepsis outcomes through innovative treatment approaches, but this specific focus on pediatric populations and the use of AI is relatively novel.
Where this research is happening
Washington, United States
- Children's Research Institute — Washington, United States (Active)
Researchers
- Principal investigator: Koutroulis, Ioannis — Children's Research Institute
- Study coordinator: Koutroulis, Ioannis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.