Preventing respiratory failure caused by pneumonia

1/1: ARREST RESPIRATORY FAILURE DUE TO PNEUMONIA (ARREST PNEUMONIA)

['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-10703403

This study is looking at whether giving a special inhaler treatment early on can help people at risk of serious breathing problems from pneumonia feel better and avoid needing more intensive care, and it’s for patients who come to the emergency room with pneumonia.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorSTANFORD UNIVERSITY (nih funded)
Locations1 site (STANFORD, UNITED STATES)
Trial IDNIH-10703403 on ClinicalTrials.gov

What this research studies

This research investigates the effectiveness of early treatment using an inhaled corticosteroid combined with a beta-agonist compared to standard care for patients at risk of acute respiratory failure due to pneumonia. The study will enroll 600 patients across 10 academic centers in the U.S. and aims to improve oxygenation and reduce the incidence of respiratory failure. By focusing on high-risk patients in emergency departments, the trial seeks to identify key risk factors and treatment responses in different patient subgroups.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults who are hospitalized with pneumonia and are at high risk for developing acute respiratory failure.

Not a fit: Patients with mild pneumonia who are not at risk for respiratory failure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatment protocols that significantly reduce the risk of respiratory failure in pneumonia patients.

How similar studies have performed: Previous studies have shown promising results with similar approaches, particularly in improving outcomes for high-risk patients with pneumonia.

Where this research is happening

STANFORD, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.