Preventing opioid use disorder before it starts
Official title: SUBTHRESHOLD OPIOID USE DISORDER PREVENTION TRIAL (CTN-0101). AUGUST 1, 2024 TO MARCH 31, 2026. N01DA-22-2253. TASK ORDER NO. 75N95024F00004 (TO20).
Funded at The Emmes Company, LLC · NIH-11211246 · Data updated 2026-11-12
This study is looking for ways to help people who are at risk of developing problems with opioid use, and it offers support and strategies to keep them safe from addiction.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | The Emmes Company, LLC NIH-funded |
| Lab location | 1 site (Rockville, United States) |
| Project start | August 1, 2024 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $113,621 |
| NIH project number | 75N95022D00017-0-759502400004-1 |
| Project ID | NIH-11211246 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are individuals at risk of developing opioid use disorder, particularly those with a history of non-medical opioid use.
✕Less likely to help
Patients who are already diagnosed with opioid use disorder may not benefit from this prevention-focused research.
What this research studies
This research focuses on developing and testing strategies to prevent opioid use disorder among individuals at risk. It is part of the NIH's HEAL initiative, which aims to address the opioid crisis by finding effective solutions for opioid misuse and addiction. The trial will involve various interventions designed to reduce the likelihood of developing an opioid use disorder, with a focus on non-medical opioid use. Patients may participate in assessments and receive support tailored to their needs during the trial period.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of opioid use disorder and improve public health outcomes.
How similar studies have gone: Previous research within the HEAL initiative has shown promise in developing effective strategies for addressing opioid misuse, indicating a potential for success in this area.
Where this research is happening
-
The Emmes Company, LLC
Rockville, United States Active
Researchers
- Principal investigator: Mccormack, Jennifer — The Emmes Company, LLC
- Study coordinator: Mccormack, Jennifer
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.