NIH-funded research R01 grant

Preventing obesity in children by managing weight gain during pregnancy

Official title: PROMISE: PReventing Obesity through healthy Maternal gestational weight gain In the Safety nEt

Funded at Oregon Health & Science University · NIH-10754886 · Data updated 2026-11-12

This study is looking at how helping women with severe obesity manage their weight during pregnancy can lead to healthier outcomes for their children, and it aims to find the best weight gain goals for these moms to support both their health and their kids' future well-being.

More Obesity research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University
NIH-funded
Lab location1 site (Portland, United States)
Project startJanuary 1, 2020
Project endDecember 31, 2025
Funding year2024
Award (this year)$564,633
NIH project number5R01DK118484-05
Project IDNIH-10754886 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are pregnant women with severe obesity, particularly those from low-income and racial/ethnic minority backgrounds.

Less likely to help

Patients who are not pregnant or those with a normal weight prior to pregnancy may not benefit from this research.

What this research studies

This research investigates how managing weight gain during pregnancy can reduce the risk of obesity in children, particularly among women with severe obesity. It focuses on establishing appropriate weight gain goals for these women to improve birth outcomes and long-term health for their children. The study utilizes a large cohort of low-income, racially, and ethnically diverse mothers and children, analyzing health data to identify the best practices for gestational weight gain. By examining over 37,000 mothers, the research aims to provide evidence-based guidelines that can be integrated into prenatal care.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes for children by reducing the prevalence of childhood obesity.

How similar studies have gone: Previous research has indicated that managing gestational weight gain can positively impact maternal and child health, suggesting that this approach has potential for success.

Where this research is happening

  • Oregon Health & Science University
    Portland, United States
    Active

Researchers

  • Principal investigator: Snowden, Jonathan M — Oregon Health & Science University
  • Study coordinator: Snowden, Jonathan M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.