Preventing obesity in children by managing weight gain during pregnancy

PROMISE: PReventing Obesity through healthy Maternal gestational weight gain In the Safety nEt

NIH-funded research Oregon Health & Science University · NIH-10754886

This study is looking at how helping women with severe obesity manage their weight during pregnancy can lead to healthier outcomes for their children, and it aims to find the best weight gain goals for these moms to support both their health and their kids' future well-being.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University NIH-funded
Lab location1 site (Portland, United States)
Project IDNIH-10754886 on NIH RePORTER

What this research studies

This research investigates how managing weight gain during pregnancy can reduce the risk of obesity in children, particularly among women with severe obesity. It focuses on establishing appropriate weight gain goals for these women to improve birth outcomes and long-term health for their children. The study utilizes a large cohort of low-income, racially, and ethnically diverse mothers and children, analyzing health data to identify the best practices for gestational weight gain. By examining over 37,000 mothers, the research aims to provide evidence-based guidelines that can be integrated into prenatal care.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant women with severe obesity, particularly those from low-income and racial/ethnic minority backgrounds.

Not a fit: Patients who are not pregnant or those with a normal weight prior to pregnancy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes for children by reducing the prevalence of childhood obesity.

How similar studies have performed: Previous research has indicated that managing gestational weight gain can positively impact maternal and child health, suggesting that this approach has potential for success.

Where this research is happening

Portland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.