Preventing lymphedema in breast cancer patients through immediate lymphatic reconstruction
Official title: Lymphedema Prevention Through Immediate Lymphatic Reconstruction
Funded at University of Tx Md Anderson Can Ctr · NIH-10942914 · Data updated 2026-11-12
This study is looking at a new surgery called immediate lymphatic reconstruction to help prevent painful swelling, known as lymphedema, in women with inflammatory breast cancer who are at higher risk after their treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $516,114 |
| NIH project number | 1R01CA292908-01 |
| Project ID | NIH-10942914 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with inflammatory breast cancer who are scheduled for axillary lymphadenectomy.
✕Less likely to help
Patients who do not have inflammatory breast cancer or who are not undergoing axillary lymphadenectomy may not benefit from this research.
What this research studies
This research investigates a surgical approach called immediate lymphatic reconstruction (ILR) to prevent lymphedema in patients with inflammatory breast cancer (IBC). IBC patients often undergo aggressive treatments that increase their risk of developing lymphedema, a condition that causes painful swelling. The study aims to assess the effectiveness of ILR performed during axillary lymphadenectomy to reduce the incidence of lymphedema and improve patient outcomes. By focusing on this high-risk group, the research seeks to identify biomarkers and evaluate long-term results of the procedure.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of lymphedema in breast cancer patients, enhancing their quality of life.
How similar studies have gone: Previous studies have shown promising results with immediate lymphatic reconstruction in other breast cancer populations, but this specific approach for IBC patients is novel.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Schaverien, Mark V — University of Tx Md Anderson Can Ctr
- Study coordinator: Schaverien, Mark V
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.