Preventing lymphedema in breast cancer patients through immediate lymphatic reconstruction

Lymphedema Prevention Through Immediate Lymphatic Reconstruction

['FUNDING_R01'] · UNIVERSITY OF TX MD ANDERSON CAN CTR · NIH-10942914

This study is looking at a new surgery called immediate lymphatic reconstruction to help prevent painful swelling, known as lymphedema, in women with inflammatory breast cancer who are at higher risk after their treatment.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TX MD ANDERSON CAN CTR (nih funded)
Locations1 site (HOUSTON, UNITED STATES)
Trial IDNIH-10942914 on ClinicalTrials.gov

What this research studies

This research investigates a surgical approach called immediate lymphatic reconstruction (ILR) to prevent lymphedema in patients with inflammatory breast cancer (IBC). IBC patients often undergo aggressive treatments that increase their risk of developing lymphedema, a condition that causes painful swelling. The study aims to assess the effectiveness of ILR performed during axillary lymphadenectomy to reduce the incidence of lymphedema and improve patient outcomes. By focusing on this high-risk group, the research seeks to identify biomarkers and evaluate long-term results of the procedure.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with inflammatory breast cancer who are scheduled for axillary lymphadenectomy.

Not a fit: Patients who do not have inflammatory breast cancer or who are not undergoing axillary lymphadenectomy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence of lymphedema in breast cancer patients, enhancing their quality of life.

How similar studies have performed: Previous studies have shown promising results with immediate lymphatic reconstruction in other breast cancer populations, but this specific approach for IBC patients is novel.

Where this research is happening

HOUSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Breast Cancer, Breast Cancer Patient

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.