Preventing Liver Cancer in People with Fatty Liver Disease
Comparative cost-effectiveness of HCC prevention in metabolic dysfunction associated fatty liver disease
This project looks at the best and most affordable ways to prevent liver cancer in people who have fatty liver disease.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11146345 on NIH RePORTER |
What this research studies
Liver cancer is a growing concern, especially for Americans, and often found too late for effective treatment. Fatty liver disease, or MAFLD, is becoming the main reason people get this type of cancer. We want to find the most effective and affordable ways to prevent liver cancer in people with MAFLD. This includes looking at different screening methods and medications like metformin and statins to see which options offer the best long-term benefits and value.
Who could benefit from this research
Good fit: This work is relevant for adults aged 21 and older who have metabolic dysfunction associated fatty liver disease (MAFLD).
Not a fit: Patients who already have advanced liver cancer or do not have MAFLD may not directly benefit from this prevention-focused work.
Why it matters
Potential benefit: If successful, this work could help doctors and patients choose the most effective and affordable strategies to prevent liver cancer, potentially saving lives.
How similar studies have performed: While current guidelines for liver cancer screening are based on older data, this work aims to provide new evidence specifically for individuals with MAFLD, where current prevention strategies are less clear.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Chhatwal, Jagpreet — Baylor College of Medicine
- Study coordinator: Chhatwal, Jagpreet
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.