Preventing infant HIV infection in Malawi

Administrative Core [Parent Title: PREVENTING INFANT INFECTIONS WITH IMPLEMENTATION SCIENCE IN MALAWI]

['FUNDING_P01'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-11325792

This program tries new ways to help stop mothers from passing HIV to their babies in Malawi by improving how prevention services are delivered.

Quick facts

Phase['FUNDING_P01']
Study typeNih_funding
SexAll
SponsorUNIV OF NORTH CAROLINA CHAPEL HILL (nih funded)
Locations1 site (CHAPEL HILL, UNITED STATES)
Trial IDNIH-11325792 on ClinicalTrials.gov

What this research studies

From a patient point of view, this program coordinates several projects that work with clinics and the Malawi Ministry of Health to make prevention services for pregnant and breastfeeding people easier to use and more reliable. The Administrative Core manages and harmonizes data, tools, and procedures across sites so results can be compared and good practices spread. It also supports program evaluations at Ministry clinics and helps train and mentor local and junior investigators. Most of the work is done through UNC Project Malawi in partnership with local hospitals and health centers.

Who could benefit from this research

Good fit: People living with HIV who are pregnant or breastfeeding and their infants who receive care at participating clinics in Malawi would be the main candidates to benefit or be included in related projects.

Not a fit: People who do not receive care at participating clinics or who live outside the regions in Malawi where the program operates may not see direct benefits from this program.

Why it matters

Potential benefit: If successful, the program could lower mother-to-child HIV transmission and keep more infants HIV-free in Malawi.

How similar studies have performed: Implementation-focused programs in other countries have reduced mother-to-child HIV transmission, but this work adapts and applies those strategies specifically to Malawi to find what works best locally.

Where this research is happening

CHAPEL HILL, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome, Acquired Immunodeficiency Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.