Preventing HPV-related cancers in American Indian and Alaska Native communities

HPV Cancer Prevention Project

NIH-funded research Indian Health Council, INC. · NIH-11174388

This project brings community-led outreach and clinic changes to increase HPV vaccination for adolescents and cervical cancer screening for women in Southern California tribal communities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIndian Health Council, INC. NIH-funded
Lab location1 site (Valley Center, United States)
Project IDNIH-11174388 on NIH RePORTER

What this research studies

Your Tribal Council and local clinics will lead culturally tailored outreach, education, and clinic workflow changes to make it easier for adolescents to get the HPV vaccine and for women to get cervical cancer screening. The Indian Health Council will use a community-engaged approach so the program reflects local priorities and is acceptable to community members. Clinics in low-resource settings will pilot multi-level interventions (education, reminders, staff training, and system changes) and track vaccination and screening uptake. Results will be shared with the community to support sustainable practices if they work.

Who could benefit from this research

Good fit: Ideal participants are American Indian and Alaska Native adolescents eligible for HPV vaccination and adult AI/AN women eligible for cervical cancer screening who receive care in the Indian Health Council service area in Southern California.

Not a fit: People who do not live in the IHC/tribal service area, are already fully vaccinated and up-to-date on screening, or whose care is outside participating clinics may not directly benefit from this project.

Why it matters

Potential benefit: If successful, the project could raise HPV vaccination and screening rates and reduce future cervical cancer cases in American Indian and Alaska Native communities.

How similar studies have performed: Community-engaged and clinic-based interventions have improved HPV vaccination and screening in other populations, though tailoring for AI/AN communities is less common and is a key part of this effort.

Where this research is happening

Valley Center, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.