NIH-funded research R01 grant

Preventing HIV Risk and Violence in Adolescent Boys

Official title: Testing the Efficacy of Safe South Africa: An Intervention to Prevent HIV Risk and Interpersonal Violence Among Adolescent Boys

Funded at American University · NIH-11520175 · Data updated 2026-11-12

A behavioral program for 15–17 year-old boys to reduce HIV risk and intimate partner violence, tested across a global site and then applied in the U.S.

More Violence research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAmerican University
NIH-funded
Lab location1 site (Washington, UNITED STATES)
Project startJuly 1, 2023
Project endApril 30, 2028
Funding year2026
Award (this year)$126,079
NIH project number3R01MH129161-04S1
Project IDNIH-11520175 on NIH RePORTER

Who could benefit from this research

Could help

Adolescent boys aged 15–17 years who are at risk for HIV and IPV and are in school settings.

Less likely to help

Adolescents outside the targeted age range or not exposed to the intervention settings may not benefit.

What this research studies

This project uses a developmentally tailored intervention based on social norms to lower HIV/STI risk and IPV among adolescent boys. It will adapt content to school environments and test its efficacy in reducing STI incidence and IPV perpetration. The study enrolls about 836 participants aged 15–17 and compares the new program to usual care to see if it lowers HIV risk behaviors and violence over time.

Why it matters

Potential benefit: If successful, the program could reduce HIV infections and violence among adolescent boys and inform scalable prevention strategies.

How similar studies have gone: Preliminary work showed acceptability and feasibility of integrated HIV-IPV prevention; this trial tests efficacy at scale.

Where this research is happening

  • American University
    Washington, United States
    Active

Researchers

  • Principal investigator: Kuo, Caroline Chia — American University
  • Study coordinator: Kuo, Caroline Chia

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.