Preventing HIV infections in mothers and infants in Malawi

Preventing Infant Infections with Implementation Science in Malawi

NIH-funded research Univ of North Carolina Chapel Hill · NIH-11063842

This study is looking for ways to help pregnant and breastfeeding women in Malawi stay HIV-free by testing new prevention methods and making it easier for them to get the care they need, all while keeping track of their health.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-11063842 on NIH RePORTER

What this research studies

This research focuses on preventing HIV infections in pregnant and breastfeeding women in Malawi, aiming to improve their engagement with healthcare services. It involves three clinical studies that will evaluate the safety and effectiveness of new HIV prevention methods, including injectable PrEP, during pregnancy and breastfeeding. The research will also establish a national registry to monitor the health outcomes of women using these prevention strategies. By addressing gaps in traditional HIV care, the project seeks to reduce the transmission of HIV from mothers to infants.

Who could benefit from this research

Good fit: Ideal candidates for this research include pregnant and breastfeeding women living with HIV or at high risk of infection in Malawi.

Not a fit: Patients who are not pregnant or breastfeeding, or those who do not reside in Malawi, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the rates of HIV infections in mothers and infants, improving health outcomes for both.

How similar studies have performed: Previous research has shown promise in using similar approaches to prevent mother-to-child transmission of HIV, indicating potential for success in this project.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.