Preventing HIV infections in mothers and infants in Malawi
Official title: Preventing Infant Infections with Implementation Science in Malawi
Funded at Univ of North Carolina Chapel Hill · NIH-11063842 · Data updated 2026-11-12
This study is looking for ways to help pregnant and breastfeeding women in Malawi stay HIV-free by testing new prevention methods and making it easier for them to get the care they need, all while keeping track of their health.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | May 15, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $1,252,461 |
| NIH project number | 5P01HD112215-03 |
| Project ID | NIH-11063842 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant and breastfeeding women living with HIV or at high risk of infection in Malawi.
✕Less likely to help
Patients who are not pregnant or breastfeeding, or those who do not reside in Malawi, may not benefit from this research.
What this research studies
This research focuses on preventing HIV infections in pregnant and breastfeeding women in Malawi, aiming to improve their engagement with healthcare services. It involves three clinical studies that will evaluate the safety and effectiveness of new HIV prevention methods, including injectable PrEP, during pregnancy and breastfeeding. The research will also establish a national registry to monitor the health outcomes of women using these prevention strategies. By addressing gaps in traditional HIV care, the project seeks to reduce the transmission of HIV from mothers to infants.
Why it matters
Potential benefit: If successful, this research could significantly reduce the rates of HIV infections in mothers and infants, improving health outcomes for both.
How similar studies have gone: Previous research has shown promise in using similar approaches to prevent mother-to-child transmission of HIV, indicating potential for success in this project.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Hosseinipour, Mina Christine — Univ of North Carolina Chapel Hill
- Study coordinator: Hosseinipour, Mina Christine
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.