Preventing HIV in men at higher risk in the U.S.
Strategies to Prevent HIV Acquisition for At-Risk Men in the US
Digital peer-led programs aim to help HIV-negative men at higher risk start and stay on PrEP.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11369762 on NIH RePORTER |
What this research studies
If you join, you would be randomly placed into one of four digital peer-delivered programs that use either one-on-one navigation, small group sessions, or combinations delivered over six months. The study enrolls about 300 PrEP-indicated HIV-negative adult men living in high-HIV areas in the Eastern and Southern US. Every three months for up to 21 months you'll complete online surveys, do remote HIV self-tests, and provide dried blood spots by mail so researchers can measure PrEP medication levels and some STIs. The team will also interview participants to learn how decisions about PrEP were made and which parts of the programs felt most useful.
Who could benefit from this research
Good fit: HIV-negative adult men who are indicated for PrEP and live in high HIV-incidence areas of the Eastern or Southern United States are ideal candidates.
Not a fit: People who already have HIV, are not eligible for PrEP, are under the eligible age, or cannot take part in digital/remote visits and home testing may not benefit from this project.
Why it matters
Potential benefit: If successful, the programs could increase PrEP starts and adherence, reducing the chance of HIV infection for men at risk.
How similar studies have performed: Previous peer-navigation and digital outreach efforts have shown promise for increasing PrEP uptake but results have been mixed, and this trial tests new combinations of those approaches.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Reisner, Sari — University of Michigan at Ann Arbor
- Study coordinator: Reisner, Sari
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.