Preventing heart rhythm problems during surgery for high-risk heart failure patients
Prophylactic Intra-Operative VT Ablation in High-Risk LVAD Candidates
This study is looking at whether a special heart procedure done during surgery can help patients who are at high risk for heart problems when getting a left ventricular assist device (LVAD), with the goal of keeping them safer and healthier after the surgery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10880442 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of a procedure called intra-operative ventricular tachyarrhythmia (VTA) ablation in patients who are at high risk for complications during left ventricular assist device (LVAD) implantation. The study aims to determine if performing this ablation during surgery can reduce the chances of developing dangerous heart rhythms after the procedure. By comparing outcomes between patients who receive the ablation and those who do not, the research seeks to provide insights into improving survival rates and reducing hospitalizations for these patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with advanced heart failure who have a history of ventricular tachyarrhythmias and are scheduled for LVAD implantation.
Not a fit: Patients without a history of ventricular tachyarrhythmias or those who are not candidates for LVAD implantation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve survival and quality of life for patients undergoing LVAD implantation by reducing the risk of life-threatening heart rhythms.
How similar studies have performed: Previous studies have shown that ablation techniques can effectively reduce recurrent ventricular tachyarrhythmias in selected patient populations, suggesting potential success for this approach.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Huang, David T — University of Rochester
- Study coordinator: Huang, David T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.