Preventing heart problems while treating cancer in adults
Official title: Primary Prevention to Reduce Cardiovascular Morbidity and Optimize Cancer Outcomes
Funded at Kaiser Foundation Research Institute · NIH-11386311 · Data updated 2026-11-12
Aims to find which cancer patients are at risk for heart problems from cancer treatments and reduce those risks while keeping cancer care effective.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project start | August 10, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $614,598 |
| NIH project number | 5R01HL151665-05 |
| Project ID | NIH-11386311 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with breast cancer treated with regimens associated with cardiotoxicity who are at high risk for cardiovascular disease.
✕Less likely to help
Patients not receiving cardiotoxic cancer therapies or those without cardiovascular risk factors may see limited benefit.
What this research studies
This project uses patient data from Kaiser Permanente to build a large dataset that links cancer info with heart risk factors and treatments. It will look at how starting heart-protective medications before or during cancer therapy affects heart health and cancer outcomes. The study plans to follow a cohort of 17,000+ breast cancer patients over time to see who develops cardiotoxicity and how prevention strategies influence long-term health. The goal is to guide personalized care so cancer treatment is delivered safely without compromising effectiveness.
Why it matters
Potential benefit: If successful, the project could lead to personalized strategies that prevent heart damage during cancer treatment while preserving cancer control.
How similar studies have gone: Previous guidelines support primary prevention in high-risk individuals, but direct evidence in cancer patients is still emerging, making this both relevant and potentially practice-changing.
Where this research is happening
-
Kaiser Foundation Research Institute
Oakland, United States Active
Researchers
- Principal investigator: Kawatkar, Aniket a — Kaiser Foundation Research Institute
- Study coordinator: Kawatkar, Aniket a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.