Preventing hearing loss caused by loud noises

Prevention of auditory nerve degeneration in noise-induced hearing loss

['FUNDING_OTHER'] · RALPH H JOHNSON VA MEDICAL CENTER · NIH-10923381

This study is looking into how loud noises can cause hearing loss, especially for military personnel, and aims to find new ways to prevent this problem so that veterans can communicate better and enjoy a better quality of life.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorRALPH H JOHNSON VA MEDICAL CENTER (nih funded)
Locations1 site (CHARLESTON, UNITED STATES)
Trial IDNIH-10923381 on ClinicalTrials.gov

What this research studies

This research focuses on understanding how excessive noise exposure leads to hearing loss, particularly among military personnel. It investigates the cellular and molecular mechanisms behind auditory nerve degeneration and aims to develop effective pre-clinical treatment strategies. By studying the roles of specific RNA binding proteins and glial cells, the research seeks to uncover new ways to prevent noise-induced hearing loss, which is a significant issue for many veterans. The ultimate goal is to improve communication abilities and quality of life for those affected.

Who could benefit from this research

Good fit: Ideal candidates for this research are active duty military personnel and veterans who have experienced noise exposure and are at risk for hearing loss.

Not a fit: Patients who have not been exposed to excessive noise or who have pre-existing hearing loss unrelated to noise exposure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that prevent hearing loss in individuals exposed to loud noises, particularly veterans.

How similar studies have performed: While there has been significant research into hearing loss, this specific approach focusing on auditory nerve degeneration and RNA binding proteins is relatively novel.

Where this research is happening

CHARLESTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.