Preventing drop-out of potential living kidney donors from Black, Hispanic, and underserved communities

Transforming Curiosity into Donation: Validating a Risk Prediction Index to Detect and Prevent Drop-Out in Potential Living Kidney Donors who are Racial/Ethnic Minorities

NIH-funded research Methodist Hospital Research Institute · NIH-11129827

This project builds a tool to spot and support Black, Hispanic, and other potential living kidney donors who might stop the donor evaluation process so more patients can get life-saving transplants.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMethodist Hospital Research Institute NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11129827 on NIH RePORTER

What this research studies

If you are thinking about donating a kidney, this project looks at why some people — especially Black, Hispanic/Latino, low-income, or non-related donors — stop the donor evaluation process and how to help them stay engaged. Researchers will analyze existing regional and national donor records to find patterns that predict who is at higher risk of dropping out. They will test and validate a risk-prediction index and then pilot targeted supports (like enhanced navigation or resources) to reduce barriers for people flagged by the tool. The goal is to make the donation process easier and fairer for underserved communities.

Who could benefit from this research

Good fit: Ideal participants are adults (21+) who are current potential living kidney donors or are expressing interest in donation, especially those who are Black, Hispanic/Latino, low-income, or not biologically related to the transplant candidate.

Not a fit: People who are not considering living kidney donation, minors, or those who are medically ineligible to donate are unlikely to benefit directly from this project.

Why it matters

Potential benefit: If successful, the project could increase living kidney donation among underrepresented groups and reduce disparities in access to transplantation.

How similar studies have performed: Prior programs using donor education and patient navigation have sometimes improved donation rates, but applying and validating a formal risk-prediction index to prevent drop-out is a newer approach.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Chronic Renal Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.