Preventing depression in new parents with a history of childhood trauma

Prevention of Perinatal Depression in Birthing People with a History of Adverse Childhood Experiences: A Type 2 Effectiveness Implementation Trial

NIH-funded research Northwestern University at Chicago · NIH-10929508

This study is looking at how to help expectant parents who have faced tough times in their childhood by providing extra mental health support during their pregnancy, especially in the last few months, to ensure both they and their baby stay healthy and happy.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10929508 on NIH RePORTER

What this research studies

This research focuses on preventing perinatal depression in individuals who have experienced adverse childhood events. It utilizes a collaborative care model to integrate mental health support into obstetric care, specifically through an evidence-based program called ROSE. By addressing the mental health needs of birthing individuals during their third trimester, the study aims to improve both maternal and child health outcomes. Participants will receive tailored interventions designed to mitigate the effects of their past experiences on their current mental health.

Who could benefit from this research

Good fit: Ideal candidates for this research are birthing individuals aged 21 and older who are in their third trimester and have a history of adverse childhood experiences.

Not a fit: Patients who do not have a history of adverse childhood experiences or are not in their third trimester may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence of perinatal depression, leading to healthier outcomes for both parents and their children.

How similar studies have performed: Previous research has shown success in using collaborative care models to address mental health issues in similar populations, indicating a promising approach.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.